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Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

Anesthesia and Neurotoxicity Research Clinical Psychology

1 paper

A Randomized Controlled Trial of Repeated Ketamine Administration for Chronic Posttraumatic Stress Disorder

Adriana Feder, Sara Costi, Sarah Rutter, Abigail B. Collins, Usha Govindarajulu, Manish K. Jha, et al.
PubMed Summary & key facts 2021 220 citations

This small randomized trial tested six IV ketamine infusions (0.5 mg/kg) given over 2 weeks versus midazolam (0.045 mg/kg) in 30 people with chronic PTSD. The ketamine group had larger drops in PTSD symptoms at 2 weeks, more people met the study’s response criteria, and ketamine was generally well tolerated.…

Anesthesia and Neurotoxicity Research Treatment of Major Depression Tryptophan and brain disorders
Summaries and links are for general information and education only. They are not a substitute for reading the original publication or for professional medical, legal, or other advice. Always refer to the linked source for the full study.