Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

4 papers

Global prevalence and burden of depressive and anxiety disorders in 204 countries and territories in 2020 due to the COVID-19 pandemic

COVID-19 Mental Disorders Collaborators
PubMed Central (PMC) Summary & key facts 2021 5,135 citations

This study reviewed surveys and used global models to measure how the COVID-19 pandemic changed rates of major depressive disorder and anxiety disorders in 2020. It found that places with higher COVID-19 infection rates and bigger drops in movement had larger increases in these disorders. The authors estimate about 53.2…

COVID-19 and Mental Health Health disparities and outcomes Long-Term Effects of COVID-19

Mindfulness-Based Interventions for Anxiety and Depression

Stefan G Hofmann, Angelina F Gómez
PubMed Central (PMC) Summary & key facts 2017 706 citations

Mindfulness-based interventions (MBIs), especially Mindfulness-Based Stress Reduction (MBSR) and Mindfulness-Based Cognitive Therapy (MBCT), teach people to pay nonjudgmental attention to the present moment. Reviews and randomized trials show MBIs can reduce anxiety and depression symptom severity across many groups, often doing better than non-evidence treatments or active controls and performing…

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes COVID-19 and Mental Health Mindfulness and Compassion Interventions

A systematic review of brief respiratory, embodiment, cognitive, and mindfulness interventions to reduce state anxiety

Chin, Phoebe, Gorman, Faye, Beck, Fraser, et al.
www.frontiersin.org Summary & key facts 2024 8 citations

This review looked at short, single-session psychological techniques aimed at lowering state anxiety. The authors found 12 randomized trials and reported that cognitive and embodiment exercises tended to reduce anxiety, while breathing-only exercises gave mixed results. Combined approaches like mindfulness showed moderate benefits when they used passive attention, but results…

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes COVID-19 and Mental Health Mindfulness and Compassion Interventions

Is your brain tired? Researchers are discovering the roots of mental fatigue

Lynne Peeples
Nature Summary & key facts 2025 0 citations

This Nature news feature by Lynne Peeples (10 December 2025) looks at new research on mental fatigue — why thinking hard can make people feel worn out. It explains that scientists are trying to build better ways to measure cognitive exhaustion. The article says those better measures could help point…

COVID-19 and Mental Health Intensive Care Unit Cognitive Disorders Long-Term Effects of COVID-19
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