Efficacy and Safety of Intranasal Ketamine for Acute Pain Management in the Emergency Setting: A Systematic Review and Meta-Analysis
This systematic review and meta-analysis pooled seven randomized trials with 1760 adults seen in emergency departments (search to 21 May 2021). It found no clear difference in short-term pain scores between intranasal (IN) ketamine and IV analgesics or placebo at 5, 15, 25, 30, and 60 minutes. The need for…