Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

2 papers

The social brain and reward: social information processing in the human striatum

Jamil P. Bhanji, Mauricio R. Delgado

This 2014 review explains that the brain’s reward system — especially a region called the striatum — responds not only to things like food or money but also to social outcomes such as praise. The authors summarize many studies showing that the striatum carries signals when people evaluate social rewards,…

Neural and Behavioral Psychology Studies Neuroendocrine regulation and behavior Neurotransmitter Receptor Influence on Behavior

Therapeutic use of psilocybin: Practical considerations for dosing and administration

Caroline A. MacCallum, Lindsay A. Lo, Carly A. Pistawka, Jagpaul Kaur Deol
Frontiers in Psychiatry Summary & key facts 2022 84 citations

This article gives health care professionals a plain overview of psilocybin-assisted psychotherapy. It summarizes how psilocybin and its active form psilocin work in the brain, how the body absorbs and clears them, practical issues for dosing and monitoring, legal and access changes, and safety concerns for medically complex patients. The…

Chemical synthesis and alkaloids Neurotransmitter Receptor Influence on Behavior Psychedelics and Drug Studies
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