Frontier mental health research: psychedelics & drug studies

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10 papers

Inclusion of people of color in psychedelic-assisted psychotherapy: a review of the literature

Timothy I. Michaels, Jennifer Purdon, Alexis Collins, Monnica T. Williams
BMC Psychiatry Summary & key facts 2018 247 citations

The authors reviewed psychedelic-assisted psychotherapy studies published from 1993 to 2017 to see how many people of color took part. They found 18 studies with about 280 people. About 82% of participants were non-Hispanic White, while only small percentages were African American, Latino, Asian, indigenous, or mixed race. Because so…

Natural Compound Pharmacology Studies Neurotransmitter Receptor Influence on Behavior Psychedelics and Drug Studies Ayahuasca LSD

MDMA-assisted psychotherapy for treatment of anxiety and other psychological distress related to life-threatening illnesses: a randomized pilot study

Philip E. Wolfson, Julane Andries, Allison A. Feduccia, Lisa Jerome, Julie B. Wang, Emily D. Williams, et al.
Scientific Reports Summary & key facts 2020 161 citations

This small, randomized, double-blind pilot study tested MDMA-assisted psychotherapy for anxiety tied to life‑threatening illness. Eighteen people were enrolled (13 got MDMA, 5 got placebo) and had two blinded 8‑hour therapy sessions, with later open‑label MDMA sessions and 6‑ and 12‑month follow-ups. The MDMA group showed a larger drop in…

Cannabis and Cannabinoid Research Natural Compound Pharmacology Studies Psychedelics and Drug Studies

Psychedelic Mushrooms in the USA: Knowledge, Patterns of Use, and Association With Health Outcomes

Richard Matzopoulos, Robert Morlock, Amy Morlock, Bernard Lerer, Leonard Lerer
Frontiers in Psychiatry Summary & key facts 2022 41 citations

Researchers ran a national online survey of U.S. adults from November 2020 to March 2021 that was weighted to represent the adult population. They asked about use of psychedelic mushrooms (psilocybin), reasons for use, and mental health. Many users said they took mushrooms for general mental health and well-being. Users…

Biochemical Analysis and Sensing Techniques Chemical synthesis and alkaloids Psychedelics and Drug Studies Psilocybin

Validation of a new instrument for assessing attitudes on psychedelics in the general population

Marija Franka Žuljević, Ivan Buljan, Mia Leskur, Mariano Kaliterna, Darko Hren, Darko Duplančić
Scientific Reports Summary & key facts 2022 29 citations

Researchers built and tested a 20-question survey called the Attitudes on Psychedelics Questionnaire (APQ) with 1,153 people in Croatia to measure how the general public thinks about psychedelics. The questions fall into four parts: legal use, effects, risks, and openness. The survey gave very consistent results, matched well with another…

Cross-Cultural and Social Analysis Psychedelics and Drug Studies Sexuality, Behavior, and Technology

Improvement in OCD symptoms associated with serotoninergic psychedelics: a retrospective online survey

Anne Buot, Cecile Pallares, A. P. Oganesyan, Charles Dauré, Valérie Bonnelle, Eric Burguière, et al.
Scientific Reports Summary & key facts 2023 27 citations

Researchers ran an online survey of about 174 people who had used psychoactive drugs to see how these drugs affected obsessive–compulsive disorder (OCD) symptoms. Participants reported that classic psychedelics were the only drugs that helped reduce OCD symptoms, and bigger immediate effects (which were linked to higher doses) were tied…

Chemical synthesis and alkaloids Neurotransmitter Receptor Influence on Behavior Psychedelics and Drug Studies

The Canadian Psychedelic Survey: Characteristics, Patterns of Use, and Access in a Large Sample of People Who Use Psychedelic Drugs

Stephanie Lake, Philippe Lucas
Psychedelic Medicine Summary & key facts 2023 26 citations

The Canadian Psychedelic Survey (CPS) surveyed 2,045 people in January 2022 about their use of psychedelic drugs in Canada. The survey found that psilocybin, MDMA, and LSD were the most used drugs. People most often used psychedelics for fun, self-exploration, general mental well-being, and personal growth. Large shares of respondents…

Chemical synthesis and alkaloids Forensic Toxicology and Drug Analysis Psychedelics and Drug Studies

Three Naturally-Occurring Psychedelics and Their Significance in the Treatment of Mental Health Disorders

Nataliya S. Vorobyeva, Alena A. Kozlova
Frontiers in Pharmacology Summary & key facts 2022 14 citations

This paper reviews research on three naturally occurring psychedelics: psilocybin, ibogaine, and N,N-dimethyltryptamine (the active part of the brew ayahuasca). It explains that these drugs work on the brain's serotonin system and summarizes growing studies that suggest they might help with problems like post-traumatic stress disorder, major depression, anxiety, and…

Chemical synthesis and alkaloids Neurotransmitter Receptor Influence on Behavior Psychedelics and Drug Studies Ayahuasca Ibogaine

Indigenous-Amazonian Traditional Medicine’s Usage of the Tobacco Plant: A Transdisciplinary Ethnopsychological Mixed-Methods Case Study

Ilana Berlowitz, Ernesto García Torres, Caroline Maake, Ursula Wolf, Chantal Martin‐Soelch
Plants Summary & key facts 2023 13 citations

Researchers reported a single case where a traditional Amazonian healer gave a weeklong, ritual treatment that included drinking a liquid made from the native tobacco plant. The patient was a 37-year-old woman with diagnosed low mood, anxiety, and attention problems plus a long-term physical health issue. The team used both…

Complementary and Alternative Medicine Studies Medicinal Plant Extracts Effects Psychedelics and Drug Studies Other

Attitudes of European psychiatrists on psychedelics: a cross-sectional survey study

Marija Franka Žuljević, Darko Hren, Dawid Storman, Mariano Kaliterna, Darko Duplančić
Scientific Reports Summary & key facts 2024 7 citations

The study surveyed 419 psychiatrists working in 33 European countries about their knowledge and attitudes toward psychedelics and psychedelic-assisted psychotherapy (PAP). Overall, psychiatrists showed general openness to psychedelics and PAP but also notable concern about risks. Younger age, being male, higher knowledge, identifying as spiritual, past personal use of psychedelics,…

Psychedelics and Drug Studies

Exploring Psychedelics for Unmet Needs in Women’s Reproductive Health

Sara Shoar, Alissa Bazinet, Chaitra Jairaj
Psychedelic Medicine Summary & key facts 2025 1 citation

While there is therapeutic potential for psychedelics in women's reproductive health issues, comprehensive research pertaining to women is lacking. While rigorous scientific inquiry into the safety, efficacy, and mechanisms of action of psychedelics in women's health is paramount, public health messaging should dispel myths and promote risk reduction strategies. Collaboration…

Chemical synthesis and alkaloids Neuroendocrine regulation and behavior Psychedelics and Drug Studies
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