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Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

Autism Spectrum Disorder Research Gene

2 papers

Socially-induced brain ‘fertilization’: play promotes brain derived neurotrophic factor transcription in the amygdala and dorsolateral frontal cortex in juvenile rats

Nakia S. Gordon, Sharon Burke, Huda Akil, Stanley J. Watson, Jaak Panksepp
Neuroscience Letters Summary & key facts 2003 108 citations

Researchers studied 32-day-old juvenile rats that were allowed 30 minutes of rough-and-tumble play. Right after play, the rats showed higher levels of BDNF messenger RNA in the amygdala and dorsolateral frontal cortex, measured with in situ hybridization. The authors suggested this could mean play helps shape brain areas tied to…

Autism Spectrum Disorder Research Child Development and Digital Technology Neuroendocrine regulation and behavior

Neurogenetic analysis of childhood disintegrative disorder

Abha R. Gupta, Alexander Westphal, Daniel Y.‐J. Yang, Catherine Sullivan, Jeffrey Eilbott, Samir Zaidi, et al.
Molecular Autism Summary & key facts 2017 24 citations

This document presents an “emerging” 2-item clinician-rated measure from the American Psychiatric Association to record how much social communication problems and restricted interests/repetitive behaviors interfere with a person’s functioning. Each domain is rated by a clinician for the past seven days on a 4-point scale from 0 (None) to 3…

Autism Spectrum Disorder Research Genetics and Neurodevelopmental Disorders Genomic variations and chromosomal abnormalities
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