Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

31 papers

The Autism-Spectrum Quotient (AQ): Evidence from Asperger Syndrome/High-Functioning Autism, Males and Females, Scientists and Mathematicians

Simon Baron‐Cohen, Sally Wheelwright, Richard Skinner, Joanne Martin, Emma Clubley

The study introduced the Autism-Spectrum Quotient (AQ), a short self-test that gives a score from 0 to 50 to measure autistic traits in adults with normal intelligence. The researchers tested four groups (58 adults with Asperger/high-functioning autism; 174 random controls; 840 Cambridge students; and 16 math Olympiad winners) and found…

Autism Spectrum Disorder Research Child Development and Digital Technology Genetics and Neurodevelopmental Disorders

“Putting on My Best Normal”: Social Camouflaging in Adults with Autism Spectrum Conditions

Laura Hull, K. V. Petrides, Carrie Allison, Paula Smith, Simon Baron‐Cohen, Meng‐Chuan Lai, et al.

Researchers interviewed 92 adults with autism to study “camouflaging,” which means hiding or changing autistic behaviors in social situations. They used thematic analysis to make a three-stage model. People said they camouflage to fit in and make connections. Camouflaging included masking (hiding traits) and compensation (using learned social techniques). Reported…

Autism Spectrum Disorder Research Child Development and Digital Technology Obsessive-Compulsive Spectrum Disorders

Sensory Processing in Autism: A Review of Neurophysiologic Findings

Elysa J. Marco, Leighton B. Hinkley, Susanna S. Hill, Srikantan S. Nagarajan
Pediatric Research Summary & key facts 2011 1,032 citations

This review looked at brain studies of how people with autism sense sounds, touch, and sights. It notes that unusual sensory reactions are very common in autism (reported in over 96% of children) and that brain measures (like ABR, EEG, MEG, and fMRI) often show differences in early auditory pathways…

Attention Deficit Hyperactivity Disorder Autism Spectrum Disorder Research EEG and Brain-Computer Interfaces

Females with ADHD: An expert consensus statement taking a lifespan approach providing guidance for the identification and treatment of attention-deficit/ hyperactivity disorder in girls and women

Susan Young, Nicoletta Adamo, Bryndís Björk Ásgeirsdóttir, Polly Branney, Michelle Beckett, William Colley, et al.
BMC Psychiatry Summary & key facts 2020 431 citations

This ADDA article explains ADHD masking — when people hide or copy others to appear "normal." Masking can help someone function but often uses a lot of mental and emotional energy. The article says masking can delay diagnosis, cause burnout or mood problems, and may help explain why women are…

Attention Deficit Hyperactivity Disorder Autism Spectrum Disorder Research Child and Adolescent Psychosocial and Emotional Development

The history of attention deficit hyperactivity disorder

Klaus W. Lange, Susanne Reichl, Katharina Lange, Lara Tucha, Oliver Tucha

The paper says the modern DSM-IV-TR idea of ADHD is relatively new, but people with symptoms like inattention, restlessness, and impulsivity were described more than 200 years ago. For example, Sir Alexander Crichton in 1798 wrote about children who could not keep their attention on one thing and were easily…

Attention Deficit Hyperactivity Disorder Autism Spectrum Disorder Research

The Neurodiversity Approach(es): What Are They and What Do They Mean for Researchers?

Patrick Dwyer
Human Development Summary & key facts 2022 417 citations

This paper says many people with ADHD have big problems with emotions. These problems include over-reacting, deep shame or guilt, and a strong sensitivity to rejection called rejection sensitive dysphoria (RSD). The author explains that emotions were often left out of ADHD research and diagnosis because they are not always…

Assistive Technology in Communication and Mobility Autism Spectrum Disorder Research Neuroethics, Human Enhancement, Biomedical Innovations

Prevalence and Early Identification of Autism Spectrum Disorder Among Children Aged 4 and 8 Years — Autism and Developmental Disabilities Monitoring Network, 16 Sites, United States, 2022

Kelly Shaw, Susan P. Williams, Mary Patrick, Miguel Valencia‐Prado, Maureen S. Durkin, Ellen M. Howerton, et al.
MMWR Surveillance Summaries Summary & key facts 2025 357 citations

This CDC report looked at how common autism spectrum disorder (ASD) was in 2022 at 16 U.S. sites and how early children were identified. Across those sites, 8-year-old children had ASD at a rate of 32.2 per 1,000 (about one in 31). The report found big differences by sex, race…

Autism Spectrum Disorder Research Child Nutrition and Feeding Issues Family and Disability Support Research

The Ritvo Autism Asperger Diagnostic Scale-Revised (RAADS-R): A Scale to Assist the Diagnosis of Autism Spectrum Disorder in Adults: An International Validation Study

Riva Ariella Ritvo, Edward Ritvo, Donald Guthrie, Max J. Ritvo, Demetra Hufnagel, William McMahon, et al.

Researchers tested the 80-question Ritvo Autism Asperger Diagnostic Scale-Revised (RAADS-R) in 779 adults at nine centers on three continents. The tool showed large score differences between 201 people with confirmed Autism Spectrum Disorder (ASD) and 578 comparison participants, and the authors concluded it is a useful tool to help clinicians…

Autism Spectrum Disorder Research Child Development and Digital Technology Genetics and Neurodevelopmental Disorders

Eye tracking in early autism research

Terje Falck‐Ytter, Sven Bölte, Gustaf Gredebäck

This review looked at eye-tracking studies of infants, toddlers, and young children with autism spectrum disorder (ASD) or at risk for ASD. Eye tracking is a non-invasive way to record where children look, and studies show early differences: reduced looking at people and faces and trouble shifting attention can appear…

Autism Spectrum Disorder Research Child Development and Digital Technology Genetics and Neurodevelopmental Disorders

Underdiagnosis of Attention-Deficit/Hyperactivity Disorder in Adult Patients

Ylva Ginsberg, Javier Quintero, Ernie Anand, Marta Casillas, Himanshu P. Upadhyaya

This review found that ADHD often continues from childhood into adulthood but is commonly missed and untreated in grown-ups. It estimates adult ADHD affects about 2.5%–5% of the general population and says fewer than 20% of adults with ADHD are diagnosed or treated. Adults with ADHD often have other mental…

Attention Deficit Hyperactivity Disorder Autism Spectrum Disorder Research Functional Brain Connectivity Studies

Miss. Diagnosis: A Systematic Review of ADHD in Adult Women

Darby E. Attoe, Emma A. Climie
Journal of Attention Disorders Summary & key facts 2023 118 citations

This systematic review looked at what happens when women live with undiagnosed ADHD and what changes after they get diagnosed as adults. The authors searched three databases and kept eight studies. They used thematic analysis and found four main themes: harms to social and emotional wellbeing, hard or strained relationships,…

Attention Deficit Hyperactivity Disorder Autism Spectrum Disorder Research Child and Adolescent Psychosocial and Emotional Development

Socially-induced brain ‘fertilization’: play promotes brain derived neurotrophic factor transcription in the amygdala and dorsolateral frontal cortex in juvenile rats

Nakia S. Gordon, Sharon Burke, Huda Akil, Stanley J. Watson, Jaak Panksepp
Neuroscience Letters Summary & key facts 2003 108 citations

Researchers studied 32-day-old juvenile rats that were allowed 30 minutes of rough-and-tumble play. Right after play, the rats showed higher levels of BDNF messenger RNA in the amygdala and dorsolateral frontal cortex, measured with in situ hybridization. The authors suggested this could mean play helps shape brain areas tied to…

Autism Spectrum Disorder Research Child Development and Digital Technology Neuroendocrine regulation and behavior
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