Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

28 papers

Mortality Rates in Patients With Anorexia Nervosa and Other Eating Disorders

Jon Arcelus, Alex J. Mitchell, Jackie Wales, Søren Nielsen
Archives of General Psychiatry Summary & key facts 2011 2,760 citations

This fact sheet reports that people with eating disorders have higher death rates than the general population. Death rates are highest for anorexia nervosa (AN). Bulimia nervosa (BN) and eating disorder not otherwise specified (EDNOS) have similar death rates. The sheet says older age at assessment was linked to higher…

Eating Disorders and Behaviors Impact of Technology on Adolescents Obsessive-Compulsive Spectrum Disorders

Prevalence of eating disorders over the 2000–2018 period: a systematic literature review

Marie Galmiche, Pierre Déchelotte, Grégory Lambert, Marie‐Pierre Tavolacci
American Journal of Clinical Nutrition Summary & key facts 2018 1,604 citations

This systematic review looked at studies from 2000–2018 that measured how common eating disorders are. The authors followed PRISMA rules and included 94 studies with accurate diagnoses and 27 studies with broader categories. Across the accurate-diagnosis studies, women had higher rates than men. Point prevalence estimates rose over time from…

Eating Disorders and Behaviors Obesity, Physical Activity, Diet Obsessive-Compulsive Spectrum Disorders

“Putting on My Best Normal”: Social Camouflaging in Adults with Autism Spectrum Conditions

Laura Hull, K. V. Petrides, Carrie Allison, Paula Smith, Simon Baron‐Cohen, Meng‐Chuan Lai, et al.

Researchers interviewed 92 adults with autism to study “camouflaging,” which means hiding or changing autistic behaviors in social situations. They used thematic analysis to make a three-stage model. People said they camouflage to fit in and make connections. Camouflaging included masking (hiding traits) and compensation (using learned social techniques). Reported…

Autism Spectrum Disorder Research Child Development and Digital Technology Obsessive-Compulsive Spectrum Disorders

Prevalence and Correlates of DSM-5–Defined Eating Disorders in a Nationally Representative Sample of U.S. Adults

Tomoko Udo, Carlos M. Grilo
Biological Psychiatry Summary & key facts 2018 768 citations

Binge eating disorder (BED) is when someone often eats a very large amount of food in a short time and feels unable to stop. It is the most common eating disorder in the U.S. and is diagnosed when binge episodes happen at least once a week for 3 months. BED…

Eating Disorders and Behaviors Obsessive-Compulsive Spectrum Disorders Workaholism, burnout, and well-being

Review of the burden of eating disorders: mortality, disability, costs, quality of life, and family burden

Daphne van Hoeken, Hans W. Hoek
Current Opinion in Psychiatry Summary & key facts 2020 716 citations

This review found that eating disorders cause a large health and social burden. In 2017 eating disorders accounted for more than 3.3 million healthy years lost worldwide. Anorexia nervosa and bulimia nervosa show rising disability, higher death rates (especially after inpatient treatment for anorexia), lower quality of life, higher costs,…

Eating Disorders and Behaviors Obesity, Physical Activity, Diet Obsessive-Compulsive Spectrum Disorders

On orthorexia nervosa: A review of the literature and proposed diagnostic criteria

Thomas M. Dunn, Steven Bratman
Eating Behaviors Summary & key facts 2015 596 citations

Orthorexia describes an extreme fixation on “healthy” eating that can harm a person’s health and life. The term was coined in 1997, but orthorexia is not an official diagnosis in the DSM-5‑TR, so how common it is and whether it is its own disorder or part of anorexia or OCD…

Child Nutrition and Feeding Issues Eating Disorders and Behaviors Obsessive-Compulsive Spectrum Disorders

Trait Extraversion and Dopamine Function

Jan Wacker, Luke D. Smillie

Psychological Types is C. G. Jung’s book that grew from about twenty years of his clinical work. It explains his idea that people have different psychological types—most famously introversion and extraversion—and describes four basic functions (thinking, feeling, sensation, intuition). Jung wrote the book to link his clinical observations with wider…

Neural and Behavioral Psychology Studies Neurotransmitter Receptor Influence on Behavior Obsessive-Compulsive Spectrum Disorders

Emotional blunting associated with SSRI-induced sexual dysfunction. Do SSRIs inhibit emotional responses?

Adam Opbroek, Pedro L. Delgado, Cindi Laukes, Cindy McGahuey, Joanna Katsanis, Francisco Moreno, et al.

This small study asked 15 people who had SSRI-related sexual problems to rate their emotions on a questionnaire. Compared with control participants, most of these patients reported weaker emotional responses across many areas, and 80% described clinically meaningful emotional blunting. The reduced emotional scores were statistically significant (p

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Obsessive-Compulsive Spectrum Disorders Treatment of Major Depression

Eating disorder outcomes: findings from a rapid review of over a decade of research

Jane Miskovic‐Wheatley, Emma Bryant, Shu Hwa Ong, Sabina Vatter, Anvi Le, Phillip Aouad, et al.
Journal of Eating Disorders Summary & key facts 2023 136 citations

This rapid review looked at research from 2009–2022 about outcomes for people with eating disorders. The authors found inconsistent definitions and limited long-term follow-up in the literature. Overall, the evidence points to low rates of remission and a high risk of death—especially for anorexia nervosa—and much of the research focuses…

Child Nutrition and Feeding Issues Eating Disorders and Behaviors Obsessive-Compulsive Spectrum Disorders

Empathy in narcissistic personality disorder: From clinical and empirical perspectives.

Arielle Baskin–Sommers, Elizabeth A. Krusemark, Elsa Ronningstam

This review examines empathy in people with narcissistic personality disorder (NPD). It says empathy is not simply missing in NPD, but is complex and varies by situation and motivation. The paper notes empathy has two parts—feeling with others (emotional empathy) and understanding others' thoughts and feelings (cognitive empathy)—and finds emotional…

Obsessive-Compulsive Spectrum Disorders Personality Disorders and Psychopathology Personality Traits and Psychology

Muscle tension in generalized anxiety disorder: Elevated muscle tonus or agitated movement?

Richard L. Hazlett, Daniel R. McLeod, Rudolf Hoehn‐Saric
Psychophysiology Summary & key facts 1994 76 citations

The study recorded electrical muscle activity (EMG) from the forehead (frontalis) and calf (gastrocnemius) in 18 women with generalized anxiety disorder (GAD) and 19 nonanxious women during baseline, a lab stressor, and recovery. The GAD group had higher average EMG levels, and during the stressor they showed a drop in…

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Obsessive-Compulsive Spectrum Disorders Psychosomatic Disorders and Their Treatments

Mentalization-Based Treatment for Pathological Narcissism

Robert P. Drozek, Brandon T. Unruh

This 2020 article reviews studies on parenting, attachment, and empathy in people with pathological narcissism and proposes using mentalization-based treatment (MBT) as a main therapy. The authors say problems with mentalization — understanding one’s own and others’ thoughts and feelings — are central to their model. They describe core MBT…

Obsessive-Compulsive Spectrum Disorders Personality Disorders and Psychopathology Personality Traits and Psychology
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