Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

20 papers

Mortality Rates in Patients With Anorexia Nervosa and Other Eating Disorders

Jon Arcelus, Alex J. Mitchell, Jackie Wales, Søren Nielsen
Archives of General Psychiatry Summary & key facts 2011 2,760 citations

This fact sheet reports that people with eating disorders have higher death rates than the general population. Death rates are highest for anorexia nervosa (AN). Bulimia nervosa (BN) and eating disorder not otherwise specified (EDNOS) have similar death rates. The sheet says older age at assessment was linked to higher…

Eating Disorders and Behaviors Impact of Technology on Adolescents Obsessive-Compulsive Spectrum Disorders

Delivering Cognitive Behavior Therapy to Young Adults With Symptoms of Depression and Anxiety Using a Fully Automated Conversational Agent (Woebot): A Randomized Controlled Trial

Kathleen Kara Fitzpatrick, Alison Darcy, Molly Vierhile
JMIR Mental Health Summary & key facts 2017 2,318 citations

This small randomized trial tested a fully automated text-based conversational agent called Woebot as a way to deliver cognitive behavioral therapy to college-age young adults with symptoms of depression and anxiety. Over 2 weeks, the Woebot group (n=34) showed a statistically larger drop in depression scores (PHQ-9) than an information-only…

Digital Mental Health Interventions Impact of Technology on Adolescents Mental Health Research Topics

Social Media Use and Its Connection to Mental Health: A Systematic Review

Fazida Karim, Azeezat Abimbola Oyewande, Lamis F Abdalla, Reem Chaudhry Ehsanullah, Safeera Khan
Cureus Summary & key facts 2020 367 citations

This systematic review looked at research on social media and mental health. The authors state that social media are responsible for making mental health problems worse. They searched 50 papers and, after applying selection rules, included 16 studies. The final papers were checked for quality and included a mix of…

Digital Mental Health Interventions Impact of Technology on Adolescents Social Media in Health Education

Instagram use is linked to increased symptoms of orthorexia nervosa

Pixie G. Turner, Carmen E. Lefevre

Researchers surveyed 680 people who followed health-food accounts online. They measured eating behaviour and orthorexia nervosa symptoms with the ORTO-15 questionnaire. Higher Instagram use was linked to more orthorexia symptoms, while other social media did not show this effect (Twitter showed a small link in exploratory tests). About 49% of…

Child Development and Digital Technology Eating Disorders and Behaviors Impact of Technology on Adolescents

Review of Smartphone Applications for the Treatment of Eating Disorders

Adrienne S. Juarascio, Stephanie M. Manasse, Stephanie P. Goldstein, Evan M. Forman, Meghan L. Butryn
European Eating Disorders Review Summary & key facts 2014 148 citations

This review looked at smartphone apps made for treating eating disorders. The authors found that research on whether these apps work is scarce. They also found that most existing apps include few proven treatment methods and do not use the special abilities of smartphones (like real-time interaction and sensors). The…

Eating Disorders and Behaviors Impact of Technology on Adolescents Mobile Health and mHealth Applications

Anorexia nervosa and the long‐term risk of mortality in women

Nathalie Auger, Brian J. Potter, Ugochinyere Vivian Ukah, Nancy Low, Mimi Israël, Howard Steiger, et al.
World Psychiatry Summary & key facts 2021 105 citations

In a study of 1,298,890 women in Quebec, 5,169 who had been hospitalized for anorexia nervosa were followed up to March 31, 2018. Women with hospital-treated anorexia had higher death rates over time than women without anorexia. The higher risk was strongest in the first 10 years after hospitalization and…

Child Nutrition and Feeding Issues Eating Disorders and Behaviors Impact of Technology on Adolescents

A Meta-Analysis of the Effects of Social Media Exposure to Upward Comparison Targets on Self-Evaluations and Emotions

Carly McComb, Eric J. Vanman, Stephanie J. Tobin
Media Psychology Summary & key facts 2023 100 citations

This meta-analysis combined 48 experimental studies with 7,679 people to test how seeing “upward” comparison targets on social media (people who seem better off) affects users’ feelings about themselves. Overall, exposure to upward comparisons produced a small but statistically significant negative effect on self-evaluations and emotions (g = −0.24, p…

Behavioral Health and Interventions Impact of Technology on Adolescents Media Influence and Health

Exercise addiction: A narrative overview of research issues

Aviv Weinstein, Attila Szabó

This review looked at research on exercise addiction from 2010 to 2022. It says there are over 1,000 papers, but exercise addiction is not a formal clinical diagnosis. Many studies use scales and questionnaires that mix up true addiction with high commitment or exercise used for other problems (like eating…

Behavioral Health and Interventions Eating Disorders and Behaviors Impact of Technology on Adolescents

Effectiveness of Digital Mental Health Tools to Reduce Depressive and Anxiety Symptoms in Low- and Middle-Income Countries: Systematic Review and Meta-analysis

Jiyeong Kim, Lois Maame Donkor Aryee, Heejung Bang, Steffi Prajogo, Yong Kyung Choi, Jeffrey S. Hoch, et al.
JMIR Mental Health Summary & key facts 2023 63 citations

The researchers did a large, careful search for studies of digital mental health tools (things like websites, phone apps, text messages, or online therapy) aimed at reducing depression and anxiety in low- and middle-income countries. They only kept randomized controlled trials, which are studies where people are randomly put into…

Digital Mental Health Interventions Impact of Technology on Adolescents Mental Health Research Topics

Screen time, impulsivity, neuropsychological functions and their relationship to growth in adolescent attention-deficit/hyperactivity disorder symptoms

Jasmina Wallace, Elroy Boers, Julien Ouellet, Mohammad H. Afzali, Patricia Conrod
Scientific Reports Summary & key facts 2023 47 citations

Researchers followed 3,779 Canadian adolescents (mean age 12.8 years, 49% girls) for five years and found that when a teen’s screen time went up in a given year, their ADHD symptoms tended to increase that same year. Impulsivity was the strongest link between screen time and ADHD symptoms. Only social…

Attention Deficit Hyperactivity Disorder Child Development and Digital Technology Impact of Technology on Adolescents

Internet-Delivered Versus Face-to-Face Cognitive Behavior Therapy for Anxiety Disorders: Systematic Review and Meta-Analysis

Narges Esfandiari, Mohammad A Mazaheri, Saeed Akbari-Zardkhaneh, Vahid Sadeghi-Firoozabadi, Mona Cheraghi
PubMed Central (PMC) Summary & key facts 2021 41 citations

This review pooled data from trials that directly compared therapist-guided internet-delivered CBT (ICBT) with face-to-face CBT for anxiety disorders. Eight randomized studies were included, and the combined result showed a near-zero difference between the two formats (Hedges' g = 0.01, 95% CI −0.16 to 0.18). The authors concluded that ICBT…

Digital Mental Health Interventions Impact of Technology on Adolescents Mental Health Research Topics

Addictive Screen Use Trajectories and Suicidal Behaviors, Suicidal Ideation, and Mental Health in US Youths

Yunyu Xiao, Meng Yuan, Timothy A. Brown, Katherine M. Keyes, J. John Mann
JAMA Summary & key facts 2025 35 citations

This study followed 4,285 U.S. children from the Adolescent Brain Cognitive Development Study to look at patterns of addictive use of social media, mobile phones, and video games from about ages 11 to 15. The researchers found that high or steadily increasing patterns of addictive use were common. Those high…

Child Development and Digital Technology Impact of Technology on Adolescents Media Influence and Health
Summaries and links are for general information and education only. They are not a substitute for reading the original publication or for professional medical, legal, or other advice. Always refer to the linked source for the full study.