Frontier mental health research: psychedelics & drug studies

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2 papers

Psychological Stress and the Human Immune System: A Meta-Analytic Study of 30 Years of Inquiry

Suzanne C Segerstrom, Gregory E Miller
PubMed Central (PMC) Summary & key facts 2004 3,257 citations

This paper is a meta-analysis of more than 300 studies in humans that looked at links between psychological stress and measures of the immune system. It found that very short, acute stressors (minutes) were tied to increases in some natural (innate) immune measures and decreases in some specific (adaptive) immune…

Health, psychology, and well-being Stress Responses and Cortisol Tryptophan and brain disorders

New Insights into the Pivotal Role of the Amygdala in Inflammation-Related Depression and Anxiety Disorder

Ping Hu, Ying Lü, Bing‐Xing Pan, Wenhua Zhang

This 2022 review looks at studies linking stress, inflammation, and changes in the amygdala to depression and anxiety. It says stress can trigger inflammation in the body and brain, that inflammation can change neurons and circuits in the amygdala, and that these changes are linked to depression- and anxiety-like signs…

Neuroinflammation and Neurodegeneration Mechanisms Stress Responses and Cortisol Tryptophan and brain disorders
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