Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

1 paper

Antidepressant effects of ketamine and the roles of AMPA glutamate receptors and other mechanisms beyond NMDA receptor antagonism

Lily R. Aleksandrova, Anthony G. Phillips, Yu Tian Wang

This paper is a clear review of how ketamine can lift severe depression quickly for some people and what we know about how it works in the brain. The authors say a single low-dose intravenous shot of ketamine can produce rapid and lasting antidepressant effects in people whose depression did…

Neuroscience and Neuropharmacology Research Treatment of Major Depression Tryptophan and brain disorders Ketamine
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