Frontier mental health research: psychedelics & drug studies

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13 papers

Global prevalence and burden of depressive and anxiety disorders in 204 countries and territories in 2020 due to the COVID-19 pandemic

COVID-19 Mental Disorders Collaborators
PubMed Central (PMC) Summary & key facts 2021 5,135 citations

This study reviewed surveys and used global models to measure how the COVID-19 pandemic changed rates of major depressive disorder and anxiety disorders in 2020. It found that places with higher COVID-19 infection rates and bigger drops in movement had larger increases in these disorders. The authors estimate about 53.2…

COVID-19 and Mental Health Health disparities and outcomes Long-Term Effects of COVID-19

Loneliness in Older Persons

Carla Perissinotto, Irena Cenzer, Kenneth E. Covinsky
Archives of Internal Medicine Summary & key facts 2012 1,225 citations

This study followed 1,604 U.S. adults older than 60 for six years. It found that people who said they felt lonely (43% of the group) were more likely to have worse day-to-day function and were more likely to die. After the researchers adjusted for age, wealth, living situation, depression, and…

Aging and Gerontology Research Health and Wellbeing Research Health disparities and outcomes

Trends in depression prevalence in the USA from 2005 to 2015: widening disparities in vulnerable groups

Andrea H. Weinberger, Misato Gbedemah, Adriana Maldonado, Denis Nash, Sandro Galea, Renée D. Goodwin
Psychological Medicine Summary & key facts 2017 704 citations

A U.S. study reported that depression became more common between 2005 and 2015. The rise was faster for young people than for older adults. The study also found growing gaps in depression rates for vulnerable groups. The authors say we do not yet know a single cause and that more…

Cardiac Health and Mental Health Health disparities and outcomes Mental Health Treatment and Access

Midlife as a pivotal period in the life course

Margie E. Lachman, Salom M. Teshale, Stefan Agrigoroaei

Using long-term data from the Midlife in the United States (MIDUS) study, the authors show that physical health, thinking skills, and well-being in midlife can change in different directions for different people. They describe these changes as multidirectional (some things get better, some worse), variable between people, and plastic (open…

Aging and Gerontology Research Health disparities and outcomes Psychological Well-being and Life Satisfaction

Midlife in the 2020s: Opportunities and challenges.

Frank J. Infurna, Denis Gerstorf, Margie E. Lachman
American Psychologist Summary & key facts 2020 343 citations

This paper says midlife (roughly ages 40–60) is an important, understudied life stage with both new opportunities and new challenges. The authors review evidence that some common ideas—like a widespread "midlife crisis"—are misleading, and they show that middle age often involves balancing many roles, linking younger and older generations, and…

Aging and Gerontology Research Health disparities and outcomes Intergenerational Family Dynamics and Caregiving

Mental Health Prevention and Promotion—A Narrative Review

Vijender Singh, Akash Kumar, Snehil Gupta
Frontiers in Psychiatry Summary & key facts 2022 211 citations

This review summarizes research on promoting mental wellbeing and preventing mental illness. It says many prevention and promotion programs work, including newer digital and community-based approaches, but most strong evidence comes from high-income countries. The review notes big gaps in real-world use, especially in low- and middle-income countries, and calls…

Digital Mental Health Interventions Health disparities and outcomes Mental Health Treatment and Access

Socioeconomic and Psychosocial Adversity in Midlife and Depressive Symptoms Post Retirement: A 21-year Follow-up of the Whitehall II Study

Marianna Virtanen, Jane E. Ferrie, G. David Batty, Marko Elovainio, Markus Jokela, Jussi Vahtera, et al.

Researchers followed 3,939 British civil servants from midlife into retirement (about 21 years) to see if problems in midlife predicted depressive symptoms after retirement. They measured midlife socioeconomic problems (job grade, satisfaction with standard of living) and psychosocial problems (job strain, number of close relationships), and later assessed depressive symptoms…

Employment and Welfare Studies Health disparities and outcomes Retirement, Disability, and Employment

The health advantage of volunteering is larger for older and less healthy volunteers in Europe: a mega-analysis

A. de Wit, Heng Qu, René Bekkers
European Journal of Ageing Summary & key facts 2022 25 citations

This is the Modern Slavery Statement for The Scott Trust, Guardian Media Group (GMG) and The Scott Trust Endowment Limited (STEL) for the year ending 31 March 2025. It describes the policies, checks, contract terms, and training they say they use to reduce the risk of modern slavery in their…

Global Health Care Issues Health disparities and outcomes Intergenerational Family Dynamics and Caregiving

Reducing the Impacts of Mental Health Stigma Through Integrated Primary Care: An Examination of the Evidence

Anderson B. Rowan, Jessica Grove, Lindsay Solfelt, Anna T. Magnante
PubMed Summary & key facts 2021 21 citations

The authors reviewed research to see if adding mental health care into primary care reduces mental health stigma. They found only seven studies that directly tested this and also looked at related research that might show stigma changes. The available evidence suggests integrated primary care could lower stigma’s effect on…

Employment and Welfare Studies Health disparities and outcomes Mental Health Treatment and Access

Relationship between depressive symptoms and anemia among the middle-aged and elderly: a cohort study over 4-year period

Congqi Liu, Ruihao Zhou, Xilin Peng, Tao Zhu, Wei Wei, Xuechao Hao
BMC Psychiatry Summary & key facts 2023 13 citations

This study used China’s CHARLS data from 2011 and 2015 to look at people aged 45 and older. In 10,179 people at baseline, higher depressive symptom scores were linked to lower hemoglobin and to having anemia. Over 4 years (5,887 people followed), people with depressive symptoms had higher odds of…

Health disparities and outcomes Maternal Mental Health During Pregnancy and Postpartum Optimism, Hope, and Well-being

Health effects and mediating mechanisms of smart wearable devices on older people: evidence from China

Enkai Guo, Song He, Lan Zheng
Frontiers in Public Health Summary & key facts 2025 10 citations

Researchers analyzed a large Chinese survey of about 22,000 people aged 60 and older from 2018 and 2020 to see how smart wearable devices relate to older people’s physical health. They found that wearing these devices was linked with better self-rated physical health. Part of that link appeared because users…

Health disparities and outcomes Retirement, Disability, and Employment Technology Use by Older Adults

The need to change: Is there a critical role of midlife adaptation in mental health later in life?

Friederike Thams, Stefanie Brassen
eLife Summary & key facts 2023 8 citations

Although late-life depression (LLD) is a serious health problem and more common than dementia in people over 60, it is underdiagnosed and undertreated. The cognitive-emotional etiology of LLD is particularly poorly understood. This is in contrast to the now extensive literature from psychology and cognitive neuroscience on the characteristics of…

Aging and Gerontology Research Health disparities and outcomes Psychological Well-being and Life Satisfaction
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