Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.
Researchers tested deep brain stimulation (DBS) in a small group of people whose depression did not get better with usual treatments. They used an implanted device that both delivered stimulation to the subcallosal cingulate (a brain area linked to mood) and recorded brain electrical signals. Around 9 out of 10…
This review combined 17 studies of deep brain stimulation (DBS) for people with treatment-resistant depression. Across studies, about 56% of patients showed a clinical response and 35% reached remission, while 14% later had recurrence. Adverse events were common (about 67%), and the two randomized trials did not show a clear,…
Spontaneous reports of vertigo or dizziness, as side-effect of certain drugs, received at our Pharmacovigilance Center, represented the 5% of all reports in 2012. Considering the high incidence of such an ADR for several drugs' classes, it can be speculated that under-reporting also affect vertigo and dizziness. Despite the fact…
Researchers ran a one-year study of vagus nerve stimulation (VNS) in about 500 adults whose depression had not improved with many previous treatments. People were randomly assigned to get real VNS or a sham (no real stimulation), and neither they nor the main study staff knew which they had. The…
