Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

Effectiveness of physical activity interventions for improving depression, anxiety and distress: an overview of systematic reviews

Ben Singh, Tim Olds, Rachel Curtis, Dorothea Dumuid, Rosa Virgara, Amanda Watson, et al.

PubMed Summary & key facts 2023 784 citations

This umbrella review pooled evidence from 97 systematic reviews (1,039 randomized trials, 128,119 participants) to examine whether physical activity affects symptoms of depression, anxiety and psychological distress in adults. Overall, physical activity produced medium-sized reductions in symptoms (median effect size for depression = -0.43, for anxiety = -0.42; distress effect…

The Effects of Tai Chi on Depression, Anxiety, and Psychological Well-Being: A Systematic Review and Meta-Analysis

Fang Wang, Eun‐Kyoung Othelia Lee, Taixiang Wu, Herbert Benson, Gregory L. Fricchione, Weidong Wang, et al.

International Journal of Behavioral Medicine Summary & key facts 2013 331 citations

This review collected studies of tai chi up to May 31, 2013 and found that many trials reported benefits for mood and psychological well-being. The authors included 37 randomized controlled trials and 5 quasi-experimental studies from English and Chinese databases. A small pooled analysis of three randomized trials that measured…

Art Therapy and Mental Health Balance, Gait, and Falls Prevention Physical Activity and Health

The effects of physical activity on cortisol and sleep: A systematic review and meta-analysis

Len De Nys, Kerry Anderson, Esther Frema Ofosu, Gemma C. Ryde, Jenni Connelly, Anna C. Whittaker

Psychoneuroendocrinology Summary & key facts 2022 227 citations

This review combined results from 10 intervention studies to see if physical activity programs change cortisol (a stress hormone) and sleep in adults. The pooled results found lower cortisol after activity programs and some improvement in sleep quality. The authors say the evidence is moderate for cortisol and low for…

Circadian rhythm and melatonin Physical Activity and Health Sleep and related disorders

Walking Psychotherapy As a Health Promotion Strategy to Improve Mental and Physical Health for Patients and Therapists: Clinical Open-Label Feasibility Trial

Nicole Koziel, Simone N. Vigod, Jennifer Price, Joanne Leung, Jennifer Hensel

PubMed Summary & key facts 2022 7 citations

This small open-label study tested whether therapists and patients could walk outside during trauma therapy sessions. Most people joined and found walking acceptable. Walking happened in about two-thirds of sessions. Some PTSD and stress scores were lower after 12 weeks, but the study had no control group and further randomized…

Cardiac Health and Mental Health Physical Activity and Health Traumatic Brain Injury Research

Walk-and-Talk Therapy Versus Conventional Indoor Therapy for Men With Low Mood: A Randomised Pilot Study

Andrea Dickmeyer, Jordan Smith, Sean Halpin, Stacey McMullen, Ryan Drew, Philip J. Morgan, et al.

PubMed Summary & key facts 2025 5 citations

This was a small randomized pilot study that tested whether outdoor “walk-and-talk” therapy is feasible and might work compared with regular indoor therapy for men with low mood. The trial included 37 men. Their average depression score (PHQ‑9) was 11.4 (SD 5.0) and their average age was 44.1 years (SD…

Art Therapy and Mental Health Physical Activity and Health Urban Green Space and Health

Associations Between Physical Activity, Sedentary Behaviour, Sleep Quality, and Anxiety Among Healthy Pain-Free Adults in Saudi Arabia: An Online Cross-Sectional Survey

Mansour Abdullah Alshehri, Areej Ali Alzylai, Joree Abdulrahman Alshehri, Lana Zaid Alsharif, Wafa Saleem Almalki, Hammad Alhasan, et al.

Sports Summary & key facts 2025 0 citations

This online study surveyed 185 healthy, pain-free adults in Saudi Arabia between December 2024 and April 2025 using validated Arabic questionnaires for physical activity, sleep quality, and anxiety. On average participants reported 1730.02 MET·min/week of physical activity and 6.77 hours/day of sedentary time. The researchers found no significant links between…

Behavioral Health and Interventions Physical Activity and Health Sleep and related disorders

Summaries and links are for general information and education only. They are not a substitute for reading the original publication or for professional medical, legal, or other advice. Always refer to the linked source for the full study.