Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

1 paper

Ketamine for Rapid Reduction of Suicidal Thoughts in Major Depression: A Midazolam-Controlled Randomized Clinical Trial

Michael F. Grunebaum, Hanga Galfalvy, Tse‐Hwei Choo, John G. Keilp, Vivek K. Moitra, Michelle S. Parris, et al.
American Journal of Psychiatry Summary & key facts 2017 412 citations

Adjunctive ketamine demonstrated a greater reduction in clinically significant suicidal ideation in depressed patients within 24 hours compared with midazolam, partially independently of antidepressant effect.

Functional Brain Connectivity Studies Treatment of Major Depression Tryptophan and brain disorders
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