Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

3 papers

Cordyceps militaris Improves Tolerance to High-Intensity Exercise After Acute and Chronic Supplementation

Katie R. Hirsch, Abbie E. Smith‐Ryan, Erica J. Roelofs, Eric T. Trexler, Meredith G. Mock
Journal of Dietary Supplements Summary & key facts 2016 28 citations

This randomized, double-blind, placebo-controlled study tested a mushroom blend containing Cordyceps militaris (4 g/day) in 28 young, recreationally active adults. After one week there were no clear group differences on most lab tests, but analysis of confidence intervals showed time-to-exhaustion (TTE) increased by about 28 seconds in the mushroom group.…

Exercise and Physiological Responses Fungal Biology and Applications Muscle metabolism and nutrition

Four Weeks of Hericium erinaceus Supplementation Does Not Impact Markers of Metabolic Flexibility or Cognition

Corey D. Grozier, Victor A Alves, Lauren G. Killen, Jeffrey D. Simpson, Eric K. O’Neal, Hunter S. Waldman

Researchers tested whether taking 10 g per day of Hericium erinaceus (Lion's Mane mushroom) for four weeks changes how the body uses fuel during exercise or affects thinking in a college-age group. In a single-blind, placebo-controlled trial, 24 participants ate muffins with either the mushroom or a placebo and completed…

Exercise and Physiological Responses Fungal Biology and Applications Muscle metabolism and nutrition

Acute Effects of Naturally Occurring Guayusa Tea and Nordic Lion’s Mane Extracts on Cognitive Performance

Michael B. La Monica, Betsy Raub, Ethan J. Ziegenfuss, Shelley Hartshorn, Jodi Grdic, Ashley Gustat, et al.
Nutrients Summary & key facts 2023 8 citations

In a randomized, double-blind, placebo-controlled crossover trial, researchers tested one single dose of 650 mg guayusa extract (AmaTea® Max), 1 g Nordic Lion’s Mane, and a placebo in healthy adults. Tests were done before ingestion and at 1 and 2 hours after. Guayusa (AMT) led to several faster and more…

Biochemical effects in animals Morinda citrifolia extract uses Muscle metabolism and nutrition
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