Amphetamines for attention deficit hyperactivity disorder (ADHD) in children and adolescents

Abstract

Most of the included studies were at high risk of bias and the overall quality of the evidence ranged from low to very low on most outcomes. Although amphetamines seem efficacious at reducing the core symptoms of ADHD in the short term, they were associated with a number of adverse events. This review found no evidence that supports any one amphetamine derivative over another, and does not reveal any differences between long-acting and short-acting amphetamine preparations. Future trials should be longer in duration (i.e. more than 12 months), include more psychosocial outcomes (e.g. quality of life and parent stress), and be transparently reported.

Topics

Attention Deficit Hyperactivity Disorder Bipolar Disorder and Treatment Neurotransmitter Receptor Influence on Behavior

Categories

Health Sciences Medicine Psychiatry and Mental health

Tags

Attention deficit Attention deficit hyperactivity disorder Developmental psychology Psychiatry Psychology