Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

10 papers

Mortality Rates in Patients With Anorexia Nervosa and Other Eating Disorders

Jon Arcelus, Alex J. Mitchell, Jackie Wales, Søren Nielsen
Archives of General Psychiatry Summary & key facts 2011 2,760 citations

This fact sheet reports that people with eating disorders have higher death rates than the general population. Death rates are highest for anorexia nervosa (AN). Bulimia nervosa (BN) and eating disorder not otherwise specified (EDNOS) have similar death rates. The sheet says older age at assessment was linked to higher…

Eating Disorders and Behaviors Impact of Technology on Adolescents Obsessive-Compulsive Spectrum Disorders

Delivering Cognitive Behavior Therapy to Young Adults With Symptoms of Depression and Anxiety Using a Fully Automated Conversational Agent (Woebot): A Randomized Controlled Trial

Kathleen Kara Fitzpatrick, Alison Darcy, Molly Vierhile
JMIR Mental Health Summary & key facts 2017 2,318 citations

This small randomized trial tested a fully automated text-based conversational agent called Woebot as a way to deliver cognitive behavioral therapy to college-age young adults with symptoms of depression and anxiety. Over 2 weeks, the Woebot group (n=34) showed a statistically larger drop in depression scores (PHQ-9) than an information-only…

Digital Mental Health Interventions Impact of Technology on Adolescents Mental Health Research Topics

Social Media Use and Its Connection to Mental Health: A Systematic Review

Fazida Karim, Azeezat Abimbola Oyewande, Lamis F Abdalla, Reem Chaudhry Ehsanullah, Safeera Khan
Cureus Summary & key facts 2020 367 citations

This systematic review looked at research on social media and mental health. The authors state that social media are responsible for making mental health problems worse. They searched 50 papers and, after applying selection rules, included 16 studies. The final papers were checked for quality and included a mix of…

Digital Mental Health Interventions Impact of Technology on Adolescents Social Media in Health Education

Review of Smartphone Applications for the Treatment of Eating Disorders

Adrienne S. Juarascio, Stephanie M. Manasse, Stephanie P. Goldstein, Evan M. Forman, Meghan L. Butryn
European Eating Disorders Review Summary & key facts 2014 148 citations

This review looked at smartphone apps made for treating eating disorders. The authors found that research on whether these apps work is scarce. They also found that most existing apps include few proven treatment methods and do not use the special abilities of smartphones (like real-time interaction and sensors). The…

Eating Disorders and Behaviors Impact of Technology on Adolescents Mobile Health and mHealth Applications

Anorexia nervosa and the long‐term risk of mortality in women

Nathalie Auger, Brian J. Potter, Ugochinyere Vivian Ukah, Nancy Low, Mimi Israël, Howard Steiger, et al.
World Psychiatry Summary & key facts 2021 105 citations

In a study of 1,298,890 women in Quebec, 5,169 who had been hospitalized for anorexia nervosa were followed up to March 31, 2018. Women with hospital-treated anorexia had higher death rates over time than women without anorexia. The higher risk was strongest in the first 10 years after hospitalization and…

Child Nutrition and Feeding Issues Eating Disorders and Behaviors Impact of Technology on Adolescents

Exercise addiction: A narrative overview of research issues

Aviv Weinstein, Attila Szabó

This review looked at research on exercise addiction from 2010 to 2022. It says there are over 1,000 papers, but exercise addiction is not a formal clinical diagnosis. Many studies use scales and questionnaires that mix up true addiction with high commitment or exercise used for other problems (like eating…

Behavioral Health and Interventions Eating Disorders and Behaviors Impact of Technology on Adolescents

Effectiveness of Digital Mental Health Tools to Reduce Depressive and Anxiety Symptoms in Low- and Middle-Income Countries: Systematic Review and Meta-analysis

Jiyeong Kim, Lois Maame Donkor Aryee, Heejung Bang, Steffi Prajogo, Yong Kyung Choi, Jeffrey S. Hoch, et al.
JMIR Mental Health Summary & key facts 2023 63 citations

The researchers did a large, careful search for studies of digital mental health tools (things like websites, phone apps, text messages, or online therapy) aimed at reducing depression and anxiety in low- and middle-income countries. They only kept randomized controlled trials, which are studies where people are randomly put into…

Digital Mental Health Interventions Impact of Technology on Adolescents Mental Health Research Topics

Internet-Delivered Versus Face-to-Face Cognitive Behavior Therapy for Anxiety Disorders: Systematic Review and Meta-Analysis

Narges Esfandiari, Mohammad A Mazaheri, Saeed Akbari-Zardkhaneh, Vahid Sadeghi-Firoozabadi, Mona Cheraghi
PubMed Central (PMC) Summary & key facts 2021 41 citations

This review pooled data from trials that directly compared therapist-guided internet-delivered CBT (ICBT) with face-to-face CBT for anxiety disorders. Eight randomized studies were included, and the combined result showed a near-zero difference between the two formats (Hedges' g = 0.01, 95% CI −0.16 to 0.18). The authors concluded that ICBT…

Digital Mental Health Interventions Impact of Technology on Adolescents Mental Health Research Topics

The Impact of Social Media on Body Image Perception in Young People

Natalia Czubaj, Martyna Szymańska, Beata Nowak, Mateusz Grajek
Nutrients Summary & key facts 2025 13 citations

This study surveyed 211 young adults about exposure to “fitspiration” or athletic images on social media and how that related to their body esteem. It found 37% of participants said such images lowered their self-esteem, with women more likely to report this (p = 0.004) and gender also linked to…

Consumer Perception and Purchasing Behavior Eating Disorders and Behaviors Impact of Technology on Adolescents

Teen Perspectives on Integrating Digital Mental Health Programs for Teens Into Public Libraries (“I Was Always at the Library”): Qualitative Interview Study

Ashley A. Knapp, Katherine Cohen, Kaylee Payne Kruzan, Rachel Kornfield, Miguel Herrera, Aderonke Bamgbose Pederson, et al.
JMIR Formative Research Summary & key facts 2024 4 citations

Researchers interviewed 16 teens who frequently used public libraries to learn how they experience anxiety and what digital tools might help them. Teens said they felt loss of control, unpredictability, and anger from anxiety and used tools like breathing exercises, journaling, and mood tracking. They viewed libraries as safe places…

Child Development and Digital Technology Digital Mental Health Interventions Impact of Technology on Adolescents
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