Cardiac arrest after ibogaine intoxication
Abstract
Ibogaine is a psychoactive herbal medication with alleged antiaddiction properties. We report a case of ibogaine intoxication mimicking Long-QT syndrome resulting in ventricular flutter and nearby cardiac arrest. A 61-year-old man experienced massive QT prolongation and ventricular flutter at a rate of 270 beats per minute requiring defibrillation after ingestion of a large dose of Ibogaine. The ingested dose of 65-70 mg/kg represents the highest survived ibogaine dose reported to date. As a result of the long plasma half-life of ibogaine, it took 7 days for the patient's QT interval to normalize.
Topics
Cardiac electrophysiology and arrhythmias Ion channel regulation and function Neurotransmitter Receptor Influence on BehaviorCategories
Cardiology and Cardiovascular Medicine Health Sciences MedicineTags
Anesthesia Cardiology Defibrillation Ingestion Internal medicine Medicine Pharmacology QT intervalSummaries and links are for general information and education only. They are not a substitute for reading the original publication or for professional medical, legal, or other advice. Always refer to the linked source for the full study.
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