Single, Repeated, and Maintenance Ketamine Infusions for Treatment-Resistant Depression: A Randomized Controlled Trial
Abstract
Repeated ketamine infusions have cumulative and sustained antidepressant effects. Reductions in depressive symptoms were maintained among responders through once-weekly infusions. These findings provide novel data on efficacious administration strategies for ketamine in patients with treatment-resistant depression. Future studies should further expand on optimizing administration to better translate the use of ketamine into clinical settings.
Topics
Mental Health Research Topics Treatment of Major Depression Tryptophan and brain disordersCategories
Health Sciences Medicine PharmacologyTags
Alternative medicine Anesthesia Antidepressant Cognition Crossover study Depression (economics) Economics Hippocampus Internal medicine Ketamine Macroeconomics Major depressive disorder Mathematics Medicine Midazolam Pathology Placebo Psychiatry Randomized controlled trial Repeated measures design Sedation Statistics Treatment-resistant depressionSummaries and links are for general information and education only. They are not a substitute for reading the original publication or for professional medical, legal, or other advice. Always refer to the linked source for the full study.
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